Social Neurobiology
Every Life Is Grievable: Ethical Heart of Care
Addiction treatment must bridge neuroscience and humanism.Understanding craving/relapse as brain-based reduces moral blame. Stigma isolates;...
Reawakening Plasticity and Connection
Compounds: psilocybin, ibogaine, ketamine → promote neuroplasticity and network integration (Nielson 2018; Davis 2020). Enhance cognitive...
GLP-1 Receptor Agonists: Metabolism Meets Motivation
Drugs such as semaglutide (Ozempic) and liraglutide (Victoza) decrease nucleus accumbens dopamine release and cue-induced craving (Sorensen et al.,...
Kappa-Opioid Receptor (KOR) Antagonists
Chronic opioid use activates dynorphin–KOR signaling → dysphoria, stress-induced craving (Carlezon & Krystal, 2016). KOR antagonists...
Emerging Treatments for Opioid Use Disorder
Despite all we know — and despite the success of methadone and buprenorphine — opioid use disorder remains one of the most lethal chronic illnesses...
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